Table 3—

Baseline characteristics of metabolic syndrome components among 9,887 initially apparently healthy women free of diabetes in the WHS

Magnesium intakeQuintile categories
P for trend
1 (lowest)2345 (highest)
n1,9771,9781,9761,9781,978
Median intake (range) (mg/day)253 (116–277)294 (277–309)325 (309–341)359 (341–383)423 (383–837)
Metabolic abnormalities*
    Abdominal obesity (%)
        Waist circumference >88 cm4845414136<0.0001
        BMI ≥30 kg/m22221161612<0.0001
    Low HDL cholesterol5551484747<0.0001
    Hypertriglyceridemia29272626270.14
    High blood pressure§3331313027<0.0001
    Abnormal glucose metabolism5.04.43.73.73.30.005
Metabolic syndrome components (%)#
    ≥1 component7774717169<0.0001
    ≥2 components5149454341<0.0001
    ≥3 components2826242321<0.0001
    ≥4 components119.59.08.46.9<0.0001
    5 components1.81.21.11.11.10.07
  • *

    * The metabolic abnormalities were defined following the National Cholesterol Education Program Adult Treatment Program III guidelines.

  • HDL cholesterol <50 mg/dl;

  • triglycerides ≥150 mg/dl;

  • §

    § blood pressure ≥135/85 mmHg;

  • the diagnosis of incident type 2 diabetes during follow-up was used as an indicator of baseline abnormal glucose metabolism;

  • #

    # central obesity was defined using waist circumference (>88 cm).