Table 4—

Relative risk of metabolic syndrome (three or more components) according to quintiles of magnesium intake in 9,887 initially apparently healthy women free of diabetes in the WHS

Quintile categories
P for trend
1 (lowest)2345 (highest)
Metabolic syndrome (waist >88 cm for obesity)
    Age, calorie-adjusted1.000.85 (0.74–0.98)0.74 (0.64–0.86)0.68 (0.59–0.79)0.61 (0.52–0.71)<0.0001
        Model 1*1.000.91 (0.78–1.05)0.82 (0.71–0.96)0.78 (0.67–0.90)0.69 (0.59–0.81)<0.0001
        Model 21.000.91 (0.78–1.06)0.84 (0.72–0.99)0.81 (0.68–0.96)0.73 (0.60–0.88)0.0008
        Model 31.000.91 (0.78–1.07)0.85 (0.72–1.01)0.84 (0.70–1.01)0.77 (0.63–0.95)0.02
        Model 4§1.000.92 (0.79–1.08)0.87 (0.74–1.03)0.83 (0.70–0.99)0.75 (0.61–0.91)0.002
Metabolic syndrome (BMI ≥30 kg/m2 for obesity)
    Age, calorie-adjusted1.000.83 (0.71–0.97)0.73 (0.62–0.86)0.64 (0.54–0.76)0.54 (0.45–0.64)<0.0001
        Model 1*1.000.89 (0.75–1.04)0.82 (0.69–0.97)0.74 (0.62–0.87)0.61 (0.51–0.73)<0.0001
        Model 21.000.90 (0.76–1.06)0.86 (0.72–1.03)0.80 (0.66–0.97)0.67 (0.54–0.83)0.0003
        Model 31.000.89 (0.75–1.06)0.84 (0.70–1.02)0.78 (0.63–0.96)0.65 (0.52–0.83)0.0004
        Model 4§1.000.91 (0.76–1.08)0.90 (0.74–1.08)0.90 (0.74–1.08)0.81 (0.66–0.99)0.0006
  • Data are median (range).

  • *

    * Model 1 adjusted for age, smoking, exercise, total calories, alcohol use, multivitamin use, and parental history of myocardial infarction before 60 years.

  • Model 2 additionally adjusted for dietary intakes of total fat, cholesterol, folate, and glycemic load.

  • Model 3 adjusted for all covariates in model 2 and dietary fiber.

  • §

    § Model 4 adjusted for all covariates in model 2 and plasma CRP concentrations.