Table 1—

Characteristics of nondiabetic mutation carriers and family members without a mutation

Nondiabetic mutation carriersFamily control subjectsP
n (M/F)13 (10/3)27 (17/10)0.48
Age when tested (years)15 (8–34)17 (8–33)0.69
BMI (kg/m2)22.21 ± 4.1824.17 ± 7.060.36
WHR0.84 ± 0.0060.83 ± 0.0090.93
Pubertal stage
    Male, pre/postpubertal5/57/100.71
    Female, pre/postpubertal1/22/80.99
Lipid profile
    Cholesterol4.3 (3.3–5.8)4.2 (2.9–5.3)0.32
    Triglycerides0.98 (0.54–2.84)0.88 (0.43–1.32)0.33
    HDL1.36 ± 0.381.28 ± 0.300.46
    LDL2.52 ± 0.792.38 ± 0.610.56
    Total/HDL3.20 (2.30–5.88)3.21 (1.91–7.74)0.89
  • Data are means ± SD or means (range), unless otherwise indicated. Age when tested was compared by the Mann-Whitney U test. BMI and WHR were compared by the t test. Categorical data were compared by the Fisher’s exact test. Cholesterol, triglycerides, and total/HDL (total-to-HDL cholesterol ratio) were compared by the Mann-Whitney U test. HDL and LDL were compared by the unpaired t test. All units are given in millimoles per liter. WHR, waist-to-hip ratio.