Table 1—

Baseline characteristics of participants by study sources and sex

FCS
FOS
LRC R
LRC H L
MRFIT-UC
Pooled
MenWomenMenWomenMenWomenMenWomenMenMenWomen
n*9781,3771,7151,7242,3592,1491,8831,4715,72512,6606,721
Current smokers (%)57.432.629.217.335.029.338.536.461.148.228.5
Diabetes (%)12.210.15.82.12.82.25.85.25.75.74.4
Age (years)6060424146484649464749
Total cholesterol (mg/dl)219241209199207207241250241229221
HDL cholesterol (mg/dl)4657445846594357424358
LDL (mg/dl)142155137124138132157167160151142
Triglycerides (mg/dl)13311612581138110242172197178117
VLDL cholesterol (mg/dl)3128271823164226393421
Non-HDL cholesterol (mg/dl)173183165141161148198193199185163
Systolic blood pressure (mmHg)140136128120126122128126137133126
BMI (kg/m2)2221272526252726272724
  • Data are mean values. Non-HDL cholesterol = total − HDL.

  • *

    * No missing values in terms of age, total cholesterol, HDL, LDL, triglycerides, and non-HDL.

  • FCS and FOS: Friedewald formula (LDL = total cholesterol − HDL − triglycerides/5) when triglycerides <400 mg/dl and direct measurement when triglycerides ≥400 mg/dl; LRC random and LRC high lipids: direct measurement; MRFIT: Friedewald formula (LDL = total cholesterol − HDL − triglycerides/5) when triglycerides <300 mg/dl and direct measurement when triglycerides ≥300 mg/dl. LRC R, Lipid Research Clinics Program Follow-up Study Random Sample; LRC H L, Lipid Research Clinics Program Follow-up Study Random Hyperlipdemia Sample; MRFIT-UC, MRFIT Usual Care Group.