Table 1—

Interrelation between 25(OH)D, BMI, and A1C in the 1958 British birth cohort (aged 45 years)

Geometric mean25(OH)D (nmol/l)
P
<2525–49.950–74.9≥75
All7.8 (561)33.4 (2,424)34.2 (2,459)24.2 (1,745)
BMI*
    Normal54.67.8 (196)29.3 (738)34.0 (857)29.0 (731)
    Overweight53.96.1 (181)32.6 (968)36.1 (1,072)25.3 (753)
    Obese47.89.3 (112)40.9 (497)32.1 (390)17.7 (215)
    Severely obese42.615.0 (72)46.1 (221)29.2 (140)9.6 (46)
P < 0.0001
A1C
All5.375.265.165.12<0.0001
BMI*
    Normal5.125.155.175.115.09<0.0001
    Overweight5.155.305.185.155.12<0.0001
    Obese5.305.555.315.215.20<0.0001
    Severely obese5.635.685.755.475.440.0001
P < 0.0001
  • Data are (%) n or geometric mean. All means are standardized by sex and season. P values test for trend in linear regression is adjusted for sex and season.

  • * Normal: BMI <25 kg/m2, n = 2,522; overweight, BMI 25–29.9 kg/m2, n = 2,974; obese: BMI 30–34.9 kg/m2, n = 1,214; and severely obese: BMI >35 kg/m2, n = 479.

  • Geometric mean of 25(OH)D.

  • Geometric mean of A1C.