Table 3—

Summary of concerns regarding the metabolic syndrome

1) Criteria are ambiguous or incomplete. Rationale for thresholds are ill defined.
2) Value of including diabetes in the definition is questionable.
3) Insulin resistance as the unifying etiology is uncertain.
4) No clear basis for including/excluding other CVD risk factors.
5) CVD risk value is variable and dependent on the specific risk factors present.
6) The CVD risk associated with the “syndrome” appears to be no greater than the sum of its parts.
7) Treatment of the syndrome is no different than the treatment for each of its components.
8) The medical value of diagnosing the syndrome is unclear.