Table 1—

Trends in the means of log fasting insulin concentrations among nondiabetic U.S. adults aged ≥20 years: NHANES III (1988–1994) and NHANES 1999–2002

NHANES III
NHANES 1999–2002
Relative change (%)Absolute changeP (df = 78)
nMean ± SEnMean ± SE
Total
    Unadjusted7,9262.12 ± 0.022,9932.24 ± 0.025.40.12<0.001
    Age adjusted7,9262.13 ± 0.022,9932.24 ± 0.024.90.10<0.001
    BMI adjusted7,9262.12 ± 0.012,9932.18 ± 0.012.80.060.003
    WC adjusted7,9262.12 ± 0.012,9932.16 ± 0.012.00.040.025
Men
    Unadjusted3,8492.13 ± 0.021,5032.28 ± 0.026.90.15<0.001
    Age adjusted3,8492.15 ± 0.021,5032.28 ± 0.026.10.13<0.001
    BMI adjusted3,8492.13 ± 0.021,5032.21 ± 0.023.90.080.001
    WC adjusted3,8492.13 ± 0.021,5032.20 ± 0.023.10.070.008
    Race/ethnicity*
Non-Hispanic white1,5892.14 ± 0.028372.27 ± 0.025.70.12<0.001
Non-Hispanic black1,0672.14 ± 0.022732.25 ± 0.045.00.110.014
Mexican American1,1932.24 ± 0.033932.43 ± 0.038.10.18<0.001
    Age (years)
20–391,7932.08 ± 0.035562.22 ± 0.037.20.15<0.001
40–599692.20 ± 0.034852.33 ± 0.036.10.130.002
≥601,0872.21 ± 0.024622.32 ± 0.034.90.110.007
    BMI (kg/m2)*
<251,5831.86 ± 0.024881.93 ± 0.023.50.070.041
25–29.91,5322.20 ± 0.026402.28 ± 0.023.60.080.013
≥307342.66 ± 0.043752.77 ± 0.044.50.120.024
    Abdominal obesity*
No2,8702.00 ± 0.029562.09 ± 0.024.80.10<0.001
Yes9792.59 ± 0.035472.66 ± 0.032.90.070.124
Women
    Unadjusted4,0772.11 ± 0.021,4902.19 ± 0.024.10.090.001
    Age adjusted4,0772.11 ± 0.021,4902.20 ± 0.023.90.080.003
    BMI adjusted4,0772.12 ± 0.011,4902.15 ± 0.021.70.040.117
    WC adjusted4,0772.11 ± 0.011,4902.13 ± 0.021.10.020.262
    Race/ethnicity*
Non-Hispanic white1,7912.07 ± 0.028282.15 ± 0.023.80.080.006
Non-Hispanic black1,2152.32 ± 0.032872.40 ± 0.043.30.080.113
Mexican American1,0712.33 ± 0.023752.41 ± 0.043.40.080.092
    Age (years)
20–391,9352.06 ± 0.024922.21 ± 0.037.30.15<0.001
40–591,0792.14 ± 0.035042.15 ± 0.040.40.010.840
≥601,0632.18 ± 0.034942.26 ± 0.033.60.080.034
    BMI (kg/m2)*
<251,6961.86 ± 0.025641.88 ± 0.021.30.020.406
25–29.91,2482.19 ± 0.024532.23 ± 0.031.90.040.225
≥301,1332.58 ± 0.024732.62 ± 0.021.30.030.322
    Abdominal obesity*
No1,9691.89 ± 0.026301.89 ± 0.020.10.000.935
Yes2,1082.42 ± 0.028602.47 ± 0.022.40.060.057
  • *

    * Adjusted for age. †Abdominal obesity: waist circumference (WC) >102 cm for men and >88 cm for women.