Table 1—

Overall and age- and sex-specific incidence densities and relative hazards of nontraumatic LEA (ICD-9: 84.1 and 84.10–84.18) in the diabetic and control groups

Variables*Control group
Diabetic group
Adjusted HR (95% CI) in association with diabetic group
Patients (n)No. of eventsID (per 100,000 patient-years) (95% CI)Patients (n)No. of eventsID (per 100,000 patient-years) (95% CI)
Men (years of age)
    <357,333007,3323586.8 (58.1–115.6)NA§
    35–4425,0171311.2 (5.1–17.3)25,010232169.6 (147.8–191.4)14.12 (8.07–24.70)
    45–5447,1143515.6 (10.4–20.8)47,078724283.1 (262.5–303.7)17.40 (12.39–24.43)
    55–6463,51210536.6 (29.6–43.7)63,4631,538460.5 (437.4–483.5)12.44 (10.21–15.17)
    65–7469,76822064.3 (55.8–72.8)69,7011,840526.9 (502.9–551.0)8.30 (7.21–9.55)
    75–8420,541109121.8 (98.9–144.6)20,511574635.7 (583.7–687.7)5.40 (4.39–6.64)
    >841,369362.3 (−8.2 to 132.8)1,36829585.2 (372.2–798.2)10.56 (3.20–34.89)
    Total234,65448544.4 (40.5–48.4)234,4634,972410.3 (398.9–421.7)9.22 (8.39–10.12)
Women (years of age)
    <357,83013.2 (−3.1 to 9.4)7,8303171.0 (46.0–96.0)22.17 (3.02–162.85)
    35–4419,31566.5 (1.3–11.8)19,310148137.0 (115.0–159.1)19.82 (8.76–44.86)
    45–5449,469156.4 (3.2–9.6)49,450512185.5 (169.4–201.6)27.92 (16.71–46.66)
    55–6483,5497318.5 (14.3–22.7)83,5251,288282.3 (266.9–297.7)15.10 (11.91–19.15)
    65–7477,40913335.0 (29.0–40.9)77,3641,747436.6 (416.1–457.1)12.44 (10.42–14.85)
    75–8425,9929985.7 (68.8–102.6)25,965697587.9 (544.2–631.5)6.93 (5.60–8.58)
    >842,02411149.6 (61.2–238.0)2,01648644.5 (462.2–826.9)4.25 (2.20–8.24)
    Total265,58833826.9 (24.0–29.8)265,4604,471317.0 (307.0–326.3)11.67 (10.44–13.05)
  • *

    * Inconsistency between total population and population summed for individual variables was due to missing information.

  • Based on Poisson assumption.

  • Based on Cox proportional hazard regression with adjustment for age, sex, geographic area, and urbanization status.

  • §

    § Not applicable (NA) due to no event of clinical end points for the control group <35 years of age. ID, incidence density.