Table 2—

Baseline levels and changes from baseline (negative values correspond to improvement) in the TSS and its individual subscores after 5 weeks of treatment (last value carried forward)

PlaceboALA600ALA1200ALA1800
TSS
    Baseline9.27 ± 1.569.44 ± 1.869.40 ± 1.649.02 ± 1.61
    Change−2.92 ± 3.18−4.85 ± 3.03*−4.50 ± 3.28*−4.70 ± 3.54*
Stabbing pain
    Baseline2.21 ± 0.772.32 ± 0.942.38 ± 0.892.03 ± 0.88
    Change−0.83 ± 1.14−1.40 ± 1.15*−1.56 ± 1.07*−1.46 ± 1.20*
Burning pain
    Baseline2.11 ± 0.872.21 ± 1.072.17 ± 1.052.15 ± 1.03
    Change−0.50 ± 1.15−1.32 ± 1.07*−1.09 ± 1.19*−1.15 ± 1.41*
Paresthesia
    Baseline2.21 ± 0.632.32 ± 0.802.12 ± 0.802.17 ± 0.69
    Change−0.80 ± 1.17−1.16 ± 1.26−0.85 ± 1.21−1.12 ± 1.20
Numbness
    Baseline2.74 ± 0.672.58 ± 0.672.73 ± 0.662.67 ± 0.72
    Change−0.79 ± 1.09−0.97 ± 1.06−0.99 ± 1.13−0.98 ± 1.16
  • Data are means ± SD.

  • *

    * P < 0.05 vs. placebo.