Table 2—

Mean baseline cognitive test scores and mean cognitive test change scores compared between those with and without hyperinsulinemia at baseline

With hyperinsulinemiaWithout hyperinsulinemiaP value
Fasting insulin (cutoff 75th percentile)
    Baseline DWR6.58 ± 1.426.83 ± 1.42<0.0001*
    DWR change score−0.254 ± 1.53−0.129 ± 1.540.0074*
    Baseline DSS43.0 ± 13.747.9 ± 13.1<0.0001*
    DSS change score−2.74 ± 7.30−2.51 ± 6.850.2954
    Baseline WF32.5 ± 12.335.1 ± 12.1<0.0001*
    WF change score−1.19 ± 7.86−0.532 ± 7.920.0064*
Fasting insulin (cutoff 12.2 mU/l)
    Baseline DWR6.59 ± 1.406.85 ± 1.43<0.0001*
    DWR change score−0.205 ± 1.57−0.134 ± 1.550.0906
    Baseline DSS43.7 ± 13.748.1 ± 13.1<0.0001*
    DSS change score−2.66 ± 7.14−2.51 ± 6.860.4348
    Baseline WF32.7 ± 12.235.3 ± 12.1<0.0001*
    WF change score−1.035 ± 7.83−0.520 ± 7.940.0164*
HOMA (cutoff 75th percentile)
    Baseline DWR6.56 ± 1.416.82 ± 1.43<0.0001*
    DWR change score−0.277 ± 1.52−0.128 ± 1.540.0025*
    Baseline DSS42.8 ± 13.847.8 ± 13.2<0.0001*
    DSS change score−2.74 ± 7.26−2.51 ± 6.870.3152
    Baseline WF32.3 ± 12.435.0 ± 12.1<0.0001*
    WF change score−1.08 ± 7.84−0.570 ± 7.930.0423*
HOMA (cutoff 2.6)
    Baseline DWR6.64 ± 1.416.86 ± 1.43<0.0001*
    DWR change score−0.211 ± 1.54−0.120 ± 1.540.0171*
    Baseline DSS44.4 ± 13.748.4 ± 13.0<0.0001*
    DSS change score−2.57 ± 7.00−2.54 ± 6.910.8335
    Baseline WF33.1 ± 12.135.5 ± 12.2<0.0001*
    WF change score−0.88 ± 7.84−0.53 ± 7.960.0799
  • Data are means ± SD.

  • *

    * Significant P values of t test.