Table 1—

Patient characteristics stratified by drug exposure

Metformin cohortSulfonylurea cohort
n6,9693,340
Age (years)
    Means ± SD61.8 ± 13.166.9 ± 13.1*
    Median (range)62.3 (30.0–105.3)68.1 (30.0–100.2)
Sex (male)3,727 (53.5)1956 (58.6)
Insulin exposure1,137 (16.3)306 (9.2)
Duration of follow-up (years)5.6 ± 1.9*5.0 ± 2.0
Mean person-years of follow-up39,02616,700
CDS8.0 (2–26)8.0 (2–22)
Overall mortality245 (3.5)162 (4.9)
  • Data are means ± SD, median (range), or n (%). n = 10,309.

  • *

    * P < 0.0001 for ANOVA;

  • P < 0.0001 for χ2;

  • P = 0.001 for χ2 test.