Table 2—

Cancer mortality and adjusted HR from multivariate Cox regression

Total nCancer deathsCancer mortality rate (per 1,000 person-years) (%)Adjusted HR (95% CI)*
Oral antidiabetics
    Metformin6,969245 (3.5)6.31.0
    Sulfonylurea3,340162 (4.9)9.71.3 (1.1–1.6)
Insulin use
    No insulin use8,866323 (3.6)6.81.0
    Insulin use1,44384 (5.8)9.91.9 (1.5–2.4)
Age (years)
    ≤53.92,57816 (0.6)1.11.0
    54.0–64.32,57875 (2.9)6.05.0 (2.9–8.6)
    64.4–73.32,576127 (4.9)8.98.9 (5.3–15.0)
    ≥73.42,577189 (7.3)15.616.9 (10.0–28.3)
Sex
    Female4,626162 (3.5)6.51.0
    Male5,683245 (4.3)8.01.5 (1.2–1.8)
Comorbidity
    CDS ≤63,181102 (3.2)6.01.0
    CDS 7–82,21084 (3.8)7.00.9 (0.7–1.2)
    CDS 9–112,513103 (4.1)7.50.9 (0.7–1.2)
    CDS ≥122,405118 (4.9)9.01.0 (0.8–1.3)
  • Data are n (%) unless otherwise indicated.

  • *

    * Adjusted for all other covariates in the table.

  • Reference category for HR.