Table 2—

Glucose (mg/dl) and C-peptide (ng/ml) values from OGTTs at visits 6 months before diagnosis and at diagnosis

Parenteral (n = 21)
Oral (n = 26)
−6 monthsDiagnosis−6 monthsDiagnosis
Fasting glucose97 ± 13110 ± 22*98 ± 14120 ± 25
2-h glucose176 ± 50279 ± 74162 ± 43274 ± 78
AUC glucose21,149 ± 3,60828,400 ± 5,02521,343 ± 3,73029,320 ± 5,835
Fasting C-peptide0.99 ± 0.581.15 ± 0.641.33 ± 0.741.80 ± 1.17*
Peak C-peptide4.04 ± 1.013.41 ± 1.474.91 ± 1.794.22 ± 2.38
AUC C-peptide371 ± 100306 ± 108441 ± 179397 ± 212
Fasting C-peptide–to–glucose ratio (×103)10 ± 610 ± 514 ± 715 ± 10
Peak C-peptide–to–2-h glucose ratio (×103)25 ± 1014 ± 833 ± 1517 ± 11
AUC C-peptide–to–glucose ratio (×103)18 ± 511 ± 521 ± 915 ± 9
  • Data are means ± SD. For difference from preceding visit:

  • * P < 0.01;

  • P < 0.001;

  • P < 0.05.