Tertiles of A1C different manifestations of PAD in people with diabetes
| A1C | P value for trend | |||||
|---|---|---|---|---|---|---|
| <5.9% | 6.0–7.4% | >7.5% | ||||
| n | 651 | 611 | 632 | |||
| Intermittent claudication cases (n = 41) | ||||||
| Model 1 | 1.00 (ref) | 3.31 (1.19–9.21) | 6.32 (2.37–16.85) | <0.001 | ||
| Model 2 | 1.00 (ref) | 3.14 (1.07–9.15) | 4.55 (1.52–13.06) | 0.007 | ||
| Hospitalization, amputation, or revascularization cases (n = 57) | ||||||
| Model 1 | 1.00 (ref) | 2.49 (1.09–5.72) | 4.38 (1.98–9.68) | <0.001 | ||
| Model 2 | 1.00 (ref) | 2.73 (1.16–6.40) | 4.56 (1.86–11.18) | <0.001 | ||
| Low ABI cases (n = 123) | ||||||
| Model 1 | 1.00 (ref) | 1.66 (1.05–2.63) | 1.61 (1.01–2.58) | 0.05 | ||
| Model 2 | 1.00 (ref) | 1.53 (0.95–2.47) | 1.64 (0.94–2.87) | 0.08 | ||
Data are RR (95% CI), unless otherwise indicated. Model 1: adjusted for age, sex, race, and ARIC field center. Model 2: adjusted for age, sex, race, and ARIC field center, LDL and HDL cholesterol, systolic blood pressure, hypertension medication use, diabetes medication, cigarette pack-years, smoking status (ever/never/former), waist-to-hip ratio, BMI, and education level.