Table 1—

Baseline characteristics of older women (NHS I), younger women (NHS II), and men (HPFS) with a history of hypertension according to thiazide use

Thiazide use
YesNo
Older women (NHS I)
    n5,24822,722
    Age (years)62.562.1
    BMI (kg/m2)28.427.5
    Physical activity (METs)17.118.1
    Currently smoking542 (10.3)2688 (11.8)
    Family history of diabetes1,324 (25.2)5,542 (24.4)
    Coronary heart disease657 (12.5)2,889 (12.7)
    Current postmenopausal hormone use2,124 (40.5)8,483 (37.3)
    Dietary intake
        Total energy (kcal/day)1,7461,726
        Alcohol (g/day)5.15.1
        Total carbohydrates (g/day)212213
        Saturated fat (g/day)1717
        Polyunsaturated fat (g/day)9.09.0
        Trans fat (g/day)2.32.3
        Magnesium (mg/day)329328
        Caffeine (mg/day)210215
        Cereal fiber (g/day)5.75.8
    Glycemic index52.752.8
Younger women (NHS II)
    n7405,158
    Age (years)39.837.7
    BMI (kg/m2)30.929.1
    Physical activity (METs)17.918.9
    Currently smoking103 (13.9)674 (13.1)
    Family history of diabetes228 (30.8)1,638 (31.8)
    Coronary heart disease17 (2.3)69 (1.3)
    Currently using
Oral contraceptive21 (2.8)313 (6.1)
Postmenopausal hormones110 (14.9)490 (9.5%
    Dietary intake
Total energy (kcal/day)1,7811,806
Alcohol (g/day)2.63.2
Total carbohydrates (g/day)219220
Saturated fat (g/day)2323
Polyunsaturated fat (g/day)1212
Trans fat (g/day)3.43.4
        Magnesium (mg/day)314313
        Caffeine (mg/day)239255
        Cereal fiber (g/day)5.45.6
        Glycemic index53.853.7
Men (HPFS)
    n4,0616,262
    Age (years)60.357.0
    BMI (kg/m2)26.526.4
    Physical activity (METs)17.118.8
    Currently smoking383 (9.4)600 (9.6)
    Family history of diabetes726 (17.9)1,074 (17.2)
    Coronary heart disease416 (10.2)863 (13.8)
    Dietary intake
Total energy (kcal/day)1,9271,964
Alcohol (g/day)13.712.8
Total carbohydrates (g/day)231235
Saturated fat (g/day)2424
Polyunsaturated fat (g/day)1313
Trans fat (g/day)2.82.8
Magnesium (mg/day)353356
Caffeine (mg/day)219216
Cereal fiber (g/day)6.76.8
    Glycemic index52.953.1
  • Data are means or n (%). MET, metabolic equivalent.