Table 1

Patient demographics at baseline

LX4211
Characteristic (statistics/category)75 mg once daily (N = 59)200 mg once daily (N = 60)200 mg twice daily (N = 60)400 mg once daily (N = 60)Placebo (N = 60)Total
(N = 299)
Age (years)
 Mean (SD)56.1 (9.6)55.6 (9.3)56.4 (8.8)56.1 (9.5)55.1 (9.8)55.9 (9.3)
Sex
 Male34 (57.6%)17 (28.3%)29 (48.3%)29 (48.3%)26 (43.3%)135 (45.2%)
 Female25 (42.4%)43 (71.7%)31 (51.7%)31 (51.7%)34 (56.7%)164 (54.8%)
Race
 Black/African American5 (8.5%)9 (15.0%)5 (8.3%)6 (10.0%)6 (10.0%)31 (10.4%)
 White48 (81.4%)51 (85.0%)53 (88.3%)51 (85.0%)49 (81.7%)252 (84.3%)
 Other*6 (10.2%)02 (3.3%)3 (5.0%)5 (8.3%)16 (5.4%)
Weight (kg)
 Mean (SD)96.2 (19.3)95.6 (19.4)95.0 (22.2)91.4 (18.6)90.6 (20.7)93.7 (20.1)
BMI (kg/m2)
 Mean (SD)33.4 (5.2)34.2 (5.8)32.9 (5.6)32.7 (5.8)32.2 (5.8)33.1 (5.7)
FPG (mg/dL)
 Mean (SD)168.5 (44.1)179.5 (53.6)181.0 (43.3)168.3 (39.2)167.1 (45.4)172.2 (45.3)
Hemoglobin A1C (%)
 Mean (SD)8.0 (0.9)8.3 (1.0)8.4 (0.9)8.1 (1.0)7.9 (0.9)8.1 (1.0)
  • * Other is comprised of American Indian, Alaska Native, Asian, or patients specified as “other” or “multiple.”