Table 1—

Baseline characteristics at entry for two cohorts, by incident diabetes status

CharacteristicExploratory cohort
Validation cohort
New diabetesNo diabetesP valueNew diabetesNo diabetesP value
n3612,3161252,295
Sex (% men)81.174.30.0278.471.50.14
Age (years)43.6 ± 5.042.2 ± 4.7<0.00144.7 ± 5.042.7 ± 4.8<0.001
BMI (kg/m2)24.8 ± 3.222.7 ± 2.9<0.00127.0 ± 4.723.5 ± 3.3<0.001
BMI 23–27.49 kg/m252.137.0<0.00139.542.1<0.01
BMI ≥27.5 kg/m219.95.7<0.00141.110.6<0.001
Waist circumference (cm)85.6 ± 8.979.2 ± 8.7<0.00192.4 ± 11.682.9 ± 9.9<0.001
Waist circumference ≥90 cm in men, ≥80 in cm women38.914.8<0.00165.630.0<0.001
Hypertension33.015.7<0.00137.612.2<0.001
Sibling or parent having diabetes53.029.1<0.00136.826.5<0.01
IFG18.06.8<0.00165.69.8<0.001
IGT test37.98.1<0.001NANANA
Triglycerides ≥200 mg/dl35.510.1<0.00145.619.5<0.001
HDL cholesterol <40 mg/dl in men, <50 mg/dl in women42.931.7<0.00118.411.80.03
Current smokers41.641.10.8632.025.30.31
Occasional drinker46.947.90.68*NANANA
Frequent drinker22.216.80.07*NANANA
  • Data are % or means ± SD. Total n = 2,667 for the exploratory cohort and total n = 2,420 for the validation cohort. P values for dichotomous outcomes were based on logistic regression adjusted for age and sex; P values for continuous outcomes were based on an F test adjusted for age and sex.

  • *

    * Compared with nondrinkers. NA, not applicable.