Table 1—

Incidence of CTS, Bell’s facial palsy, and other peripheral nerve disorders during study period up to 10 years before diabetes diagnosis

nPerson-yearsEvents (no.)Incidence rate (per 100,000 person-years)Relative risk (95% CI)P valueAdjusted relative risk (95% CI)P value
CTS
    Pre-diabetic subjects2,61322,82097425.11.63 (1.26–2.11)<0.0011.36 (1.02–1.81)*0.039
    Control subjects5,24645,393118260.0
Bell’s facial palsy
    Pre-diabetic subjects2,63623,4251981.11.96 (1.04–3.70)0.0391.64 (0.87–3.11)0.128
    Control subjects5,28246,1631941.2
Other peripheral nerve disorders
    Pre-diabetic subjects2,63223,29629124.51.02 (0.65–1.58)0.9390.96 (0.60–1.52)0.857
    Control subjects5,28146,03856121.6
  • Results after omitting 82 prevalent cases of CTS, 23 prevalent cases of Bell’s palsy, or 28 prevalent cases of “other peripheral nervous system disorders.”

  • *

    * Adjusted for sex, age-group, BMI category, and whether subject had history of thyroid disorders, wrist fractures, rheumatoid arthritis, and osteoarthritis before CTS diagnosis.

  • Adjusted for sex, age-group, and BMI category only.