Table 1—

Demographics and clinical variables in all subjects, LIS, LIR, OIR, men, and women

AllLISLIROIRMenWomen
n17753605675102
Age (years)52.3 ± 9.949.6 ± 8.053.8 ± 11.4*53.2 ±9.652.6 ± 10.252.0 ± 9.8
Sex (male/female)75/10218/3527/3325/31
BMI (kg/m2)26.4 ± 4.323.4 ± 2.324.3 ± 1.831.0 ± 3.4*26.8 ± 3.526.2 ± 4.8
Waist circumference (cm)87.2 ± 13.277.9 ± 8.583.7 ± 9.2*99.3 ± 11.1*94.9 ± 10.681.9 ± 12.2
WHR0.84 ± 0.090.80 ± 0.080.83 ± 0.09*0.89 ± 0.08*0.92 ± 0.060.78 ± 0.06
SCF area (cm2)195.8 (135.6)125.7 (102.7)179.6 (114.1)*299.1 (164.1)*166.9 (117.3)§225.9 (162.9)
IAF area (cm2)88.4 (84.9)43.3 (36.4)76.8 (69.3)*140.6 (57.9)*113.8 (86.9)71.9 (79.1)
Systolic blood pressure (mmHg)118 ± 12114 ± 10117 ± 10123 ± 12*120 ± 11117 ± 12
SI (×10−5 min−1/[pmol/l])5.65 (4.61)9.35 (3.94)5.04 (2.54)*3.59 (2.10)*4.93 (4.88)6.03 (4.18)
Fasting plasma glucose (mmol/l)5.4 ± 0.45.3 ± 0.45.4 ± 0.4*5.6 ± 0.5*5.6 ± 0.45.3 ± 0.4
Triglycerides (mmol/l)1.4 (0.79)0.99 (0.72)1.4 (0.5)*1.6 (0.75)*1.4 (0.82)1.3 (0.75)
HDL cholesterol (mmol/l)1.4 ± 0.41.5 ± 0.41.3 ± 0.4*1.2 ± 0.4*1.2 ± 0.31.5 ± 0.4
Alcohol intake (drinks/week)1.0 (3.0)1.0 (2.0)1.0 (4.0)1.5 (4.0)2.0 (7.0)#1.0 (2.0)
  • Data are means ± SD or median (IQR). Normal ranges: GGT <51 IU/l, ALT <40 IU/l, and AST <38 IU/l. LIS vs. LIR vs. OIR: ANOVA

  • *

    * P < 0.05 vs. LIS;

  • P < 0.05 vs. LIR (eight OIR subjects were excluded from this analysis because of the small number). Men vs. women: t test

  • P < 0.0001,

  • §

    § P < 0.005,

  • P < 0.05; Mann Whitney U test

  • #

    # P < 0.05.