Table 1—

RR of type 2 diabetes between quartiles of serum 25OHD concentration (n = 4,097)

Serum 25OHD quartile*
P for trend
1234
N1,0511,079986981
n52623930
Mean serum 25OHD (nmol/l)22.435.547.970.9
Model
    11.001.18 (0.81–1.72)0.79 (0.51–1.22)0.60 (0.36–0.98)0.01
    21.001.15 (0.79–1.69)0.83 (0.53–1.29)0.70 (0.42–1.16)0.07
    31.001.10 (0.75–1.61)0.80 (0.51–1.25)0.67 (0.41–1.11)0.05
    41.001.23 (0.80–1.89)0.97 (0.59–1.58)0.58 (0.32–1.06)0.06
  • Data are RR or RR (95% CI) unless otherwise indicated.

  • *

    * Quartile 1, <30 nmol/l; 2, 30–41 nmol/l; 3, 42–55 nmol/l; and 4, >55 nmol/l.

  • Model 1: RRs adjusted for age (continuous variable), sex, and month of collecting blood samples; N (all data) = 4,097 and n (type 2 diabetes cases) = 183. Model 2: RRs were adjusted for all of the factors in model 1 plus BMI (<23, 23–24.9, 25–27.4, 27.5–29.9, or ≥30 kg/m2), leisure-time exercise (little, occasionally, or regularly), smoking (never smokers, ex-smokers, a cigar or pipe or <20, 20–29, or >29 cigarettes/day), and education (<7, 7–9, 10–12, or >12 years); N = 4,083 and n = 183. Model 3: RRs were adjusted for all of the factors in model 2 plus blood pressure (normotension, borderline hypertension, mild hypertension, or definite hypertension); N = 4,030 and n = 181. Model 4: RRs were adjusted for all of the factors in model 2, and the first 5 years of follow-up were excluded; N = 4,044 and n = 144.