Serum 25OHD quartile* | P for trend | |||||||
---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | |||||
N | 1,051 | 1,079 | 986 | 981 | — | |||
n | 52 | 62 | 39 | 30 | — | |||
Mean serum 25OHD (nmol/l) | 22.4 | 35.5 | 47.9 | 70.9 | — | |||
Model† | ||||||||
1 | 1.00 | 1.18 (0.81–1.72) | 0.79 (0.51–1.22) | 0.60 (0.36–0.98) | 0.01 | |||
2 | 1.00 | 1.15 (0.79–1.69) | 0.83 (0.53–1.29) | 0.70 (0.42–1.16) | 0.07 | |||
3 | 1.00 | 1.10 (0.75–1.61) | 0.80 (0.51–1.25) | 0.67 (0.41–1.11) | 0.05 | |||
4 | 1.00 | 1.23 (0.80–1.89) | 0.97 (0.59–1.58) | 0.58 (0.32–1.06) | 0.06 |
Data are RR or RR (95% CI) unless otherwise indicated.
↵* Quartile 1, <30 nmol/l; 2, 30–41 nmol/l; 3, 42–55 nmol/l; and 4, >55 nmol/l.
↵† Model 1: RRs adjusted for age (continuous variable), sex, and month of collecting blood samples; N (all data) = 4,097 and n (type 2 diabetes cases) = 183. Model 2: RRs were adjusted for all of the factors in model 1 plus BMI (<23, 23–24.9, 25–27.4, 27.5–29.9, or ≥30 kg/m^{2}), leisure-time exercise (little, occasionally, or regularly), smoking (never smokers, ex-smokers, a cigar or pipe or <20, 20–29, or >29 cigarettes/day), and education (<7, 7–9, 10–12, or >12 years); N = 4,083 and n = 183. Model 3: RRs were adjusted for all of the factors in model 2 plus blood pressure (normotension, borderline hypertension, mild hypertension, or definite hypertension); N = 4,030 and n = 181. Model 4: RRs were adjusted for all of the factors in model 2, and the first 5 years of follow-up were excluded; N = 4,044 and n = 144.