Table 1—

Estimates of glycemic characteristics at the end of each trimester for type 1 and type 2 diabetes, obtained from generalized linear mixed effects models

Glycemic measureTrimester 1Trimester 2Trimester 3P
Euglycemia
    Percentage of time 70–140 mg/dl (hours per 24 h)
Type 143.2% (10.4 h)49.3% (11.8 h)56.3% (13.5 h)Diabetes type: 0.0001
Type 257.6% (13.8 h)65.8% (15.8 h)75.1% (18.0 h)Gestational period: 0.0001
Hyperglycemia
    Percentage of time >140 mg/dl (hours per 24 h)
Type 140.5% (9.7 h)36.4% (8.7 h)32.7% (7.8 h)Diabetes type: 0.005
Type 232.8% (7.9 h)19.5% (4.7 h)11.6% (2.8 h)Gestational period: 0.007
    Area under the curve >140 mg/dl
Type 123.0417.2812.78Diabetes type: 0.001
Type 214.045.762.52Gestational period: 0.0002
    Percentage of time >200 mg/dl (hours per 24 h)
Type 116% (3.8 h)11.8% (2.8 h)8.7% (2.0 h)Diabetes type: 0.0004
Type 27.9% (1.9 h)2.9% (0.7 h)1.0% (0.2 h)Gestational period: 0.0006
Hypoglycemia
    Percentage of time <70 mg/dl (hours per time period)
Overall (24 h)
    Type 114.6% (3.5 h)13.7% (3.3 h)12.9% (3.0 h)Diabetes type: 0.04
    Type 210.2% (2.4 h)9.6% (2.3 h)9.1% (2.2 h)Gestational period: NS
Nocturnal (2200–0600 h)
    Type 114.6% (1.1 h)16.2% (1.3 h)18.1% (1.5 h)Diabetes type: NS
    Type 214.8% (1.1 h)16.5% (1.3 h)18.4% (1.5 h)Gestational period: NS
Area under the curve <70 mg/dl
    Type 12.522.161.80Diabetes type: 0.02
    Type 21.441.261.08Gestational period: NS
    Percentage of time <50 mg/dl (hours per time period)
Overall (24 h)
    Type 15.7% (1.4 h)4.6% (1.1 h)3.7% (0.9 h)Diabetes type: 0.02
    Type 23.0% (0.7 h)2.5% (0.6 h)2.0% (0.5 h)Gestational period: NS
Nocturnal (2200–0600 h)
    Type 17.3% (0.6 h)6.3% (0.5 h)5.4% (0.4 h)Diabetes type: NS
    Type 25.1% (0.4 h)4.4% (0.3 h)3.8% (0.3 h)Gestational period: NS
Mean blood glucose (mg/dl)
    Type 1137128119Diabetes type: 0.08
    Type 2126117106Gestational period: 0.009
A1C (%)
    Type 16.846.375.90Diabetes type: NS
    Type 26.566.095.62Gestational period: 0.004