Table 2—

Results of repeat adenosine 99mTc-sestamibi SPECT imaging

DIAD-2 adenosine SPECT
Blinded panel readComputer quantification
n358358
Normal315 (88)321 (90)
Abnormal43 (12)36 (10)
Regional perfusion abnormalities24 (7)*18 (5)
    Small11 (3)4 (1)
    Moderate/large13 (4)14 (4)
Nonperfusion abnormalities19 (5)§
    Positive ECG15 (4)
    Transient dilation2 (0.5)
    Left ventricular dysfunction2 (0.5)**
DIAD-1 vs. DIAD-2 categorization
    Normal-normal259 (72)274 (77)
    Normal-abnormal28 (8)25 (7)
    Abnormal-abnormal15 (4)12 (3)
    Abnormal-normal56 (16)47 (13)
  • Data are n (%).

  • *

    * New abnormalities in DIAD-2 analysis: 18;

  • New abnormalities in DIAD-2 analysis: 9;

  • New abnormalities in DIAD-2 analysis: 9;

  • §

    § New abnormalities in DIAD-2 analysis: 12;

  • New abnormalities in DIAD-2 analysis: 9;

  • New abnormalities in DIAD-2 analysis: 2;

  • **

    ** New abnormalities in DIAD-2 analysis: 1.