Table 3—

Multivariate RRs of type 2 diabetes according to categories of BMI, waist circumference, and physical activity from the Nurses’ Health Study from 1986 through 2002

MET hours of activity per week
<2.12.1–4.64.7–10.410.5–21.7≥21.8P for trend
BMI (kg/m2)
    <25
        Multivariate-adjusted RR*2.08 (1.66–2.61)1.64 (1.29–2.08)1.50 (1.20–1.88)1.58 (1.28–1.96)1 (Ref.)<0.001
    25–29.9
        Multivariate-adjusted RR*6.87 (5.67–8.33)6.30 (5.18–7.66)5.10 (4.20–6.21)5.35 (4.41–6.48)4.76 (3.92–5.79)<0.001
    30
        Multivariate-adjusted RR*16.75 (13.99–20.04)15.76 (13.06–19.01)13.01 (10.74–15.75)12.93 (10.64–15.71)10.74 (8.74–13.18)<0.001
MET hours of activity per week
Inactive (<2)Moderate (2.0–5.9)Vigorous (≥6)
Waist circumference tertiles (inches)
    <28
        Multivariate-adjusted RR*2.01 (1.08–3.73)1.20 (0.58–2.49)1 (Ref.)
        Multivariate RR further adjusted for continuous BMI*2.16 (1.15–4.04)0.99 (0.44–2.24)1 (Ref.)
    29–31
        Multivariate-adjusted RR*5.24 (3.52–7.82)4.57 (3.08–6.79)3.73 (2.62–5.32)
        Multivariate RR further adjusted for continuous BMI*4.22 (2.79–6.36)3.75 (2.50–5.64)3.10 (2.15–4.46)
    ≥32
        Multivariate-adjusted RR*22.26 (15.75–31.45)19.87 (14.04–28.11)15.92 (11.34–22.35)
        Multivariate RR further adjusted for continuous BMI*10.26 (7.14–14.74)9.74 (6.78–13.98)8.22 (5.77–11.71)
  • Data are RR (95% CI).

  • *

    * Adjusted for age (5-year interval), smoking status (never, past, or current [1–14, 15–24, or 25 cigarettes/day]), alcohol consumption (0, 0.1–4.9, 5–14.9, or ≥15 g/day), menopausal status and postmenopausal hormone use, and family history of diabetes.