Table 1—

Age and age-adjusted mean levels of selected risk factors according to sex and case/control status

Risk factor at baselineWomen
Men
P value for interaction*
Case subjectsControl subjectsP valueCase subjectsControl subjectsP value
n5215639117
Age (years)61.6 ± 10.856.5 ± 10.30.00163.0 ± 11.360.9 ± 11.40.2770.215
BMI (kg/m2)28.8 ± 5.427.5 ± 5.30.13625.7 ± 4.924.7 ± 3.50.1610.260
Waist (cm)91.3 ± 12.986.2 ± 12.30.01389.7 ± 12.886.9 ± 9.20.1360.278
CRP (μg/ml)4.7 ± 3.54.1 ± 2.90.2362.5 ± 2.61.8 ± 1.80.0470.951
Interleukin-6 (pg/ml)3.0 ± 2.12.9 ± 1.60.7341.8 ± 1.22.1 ± 1.80.2360.337
E-selectin (ng/ml)51.2 ± 17.945.5 ± 18.20.05840.1 ± 16.942.0 ± 16.60.5290.033
sICAM-1 (ng/ml)274.7 ± 61.4252.5 ± 52.80.012252.2 ± 50.7255.8 ± 57.70.7330.016
PAI-1 (ng/ml)37.3 ± 18.826.1 ± 16.3<0.00127.5 ± 15.628.4 ± 17.80.7690.002
Adiponectin (ng/ml)9.1 ± 5.211.4 ± 5.00.0046.8 ± 4.47.2 ± 4.00.5480.111
ln triglycerides (mg/dl)4.7 ± 0.54.5 ± 0.50.0244.7 ± 0.64.6 ± 0.50.1720.227
Fasting glucose (mg/dl)91.9 ± 4.888.3 ± 5.5<0.00194.0 ± 3.690.6 ± 5.1<0.0010.833
ln ACR (mg/g)1.91 ± 0.81.79 ± 0.70.7941.4 ± 0.91.4 ± 0.70.2650.810
HOMA-IR3.3 ± 1.62.8 ± 1.30.0433.7 ± 1.93.1 ± 1.80.0800.965
Hypertension (%)†49.727.00.00461.147.10.1100.304
  • Data are means ± SD.

  • *

    * Interaction of sex by case-control status. †Hypertension was defined as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg or receiving treatment.