Table 3—

Multivariate models of hyperglycemic progression

Model A
Model B
Model C
Model D
OR95% CIP valueOR95% CIP valueOR95% CIP valueOR95% CIP value
Progressed to original IFG3.112.43–3.98<0.0001
Initially added IFG1.120.88–1.420.352
Initially original IFG1.611.12–2.320.010
Initial FPG in stage (mg/dl)1.081.05–1.12<0.00011.081.04–1.130.00031.071.04–1.10<0.00011.071.04–1.10<0.0001
Age (per 10 years)0.980.93–1.020.3110.920.86–0.990.0200.920.87–0.980.0150.920.88–0.970.002
Female sex1.050.87–1.280.6111.471.11–1.930.0071.331.02–1.720.0321.441.17–1.770.781
History of CVD1.281.05–1.550.0130.900.68–1.190.4550.990.76–1.300.9591.030.83–1.280.781
Current smoker0.990.80–1.230.9441.511.15–1.990.0031.170.89–1.530.2551.241.00–1.540.047
BMI (kg/m2)1.031.02–1.05<0.00011.041.02–1.06<0.00011.031.02–1.05<0.00011.041.03–1.06<0.0001
Systolic BP (per 5 mmHg)1.041.00–1.080.0661.101.04–1.16<0.00011.081.03–1.140.0011.091.05–1.14<0.0001
HDL cholesterol (per 5 mg/dl)0.930.89–0.960.00010.880.83–0.93<0.00010.880.84–0.93<0.00010.870.84–0.91<0.0001
LDL cholesterol (per 5 mg/dl)1.010.99–1.020.3400.970.95–0.990.0030.990.97–1.010.4111.020.97–1.000.030
Triglycerides (per 50 mg/dl)1.011.00–1.020.0021.011.00–1.020.0261.031.01–1.040.00031.011.01–1.020.001
  • Model A: progression from added to original IFG; Model B: progression from added IFG to diabetes; Model C: progression from original IFG to diabetes; Model D: progression from either stage to diabetes. BP, blood pressure; CVD, cardiovascular disease; OR, odds ratio.