Table 4—

Adjusted* OR (95% CI) of diabetes by tertiles of sex steroid hormone concentrations after mutually adjusting the hormones, NHANES III

Q1 (lowest)Q2Q3 (highest)P trend
Total testosterone (ng/ml) (≤4.54, 4.55–6.27, >6.27)1.99 (0.76–5.19)0.64 (0.15–2.65)1.00 (reference)0.014
Estradiol (E2) (pg/ml) (≤31.90, 31.91–40.26, >40.26)0.71 (0.24–2.07)0.99 (0.29–3.33)1.00 (reference)0.33
SHBG (nmol/l) (≤28.03, 28.04–43.50, >43.50)0.48 (0.20–1.18)0.76 (0.35–1.63)1.00 (reference)0.32
  • *

    * Simultaneously adjusted for age, race/ethnicity, BMI, waist-to-hip ratio, and the other two hormones.