Table 2—

OGTT-derived models for calculations of SI and AIR in nondiabetic individuals without IGT

Name of modelBlood sampling time points for measurements of plasma glucose and serum insulin during an OGTTEquation
BIGTT-SI|0-30-1200, 30, and 120 minexp[4.90 − (0.00402 · I0) − (0.000556 · I30) − (0.00127 · I120) − (0.152 · G0) − (0.00871 · G30) − (0.0373 · G120) − (0.145 · sex) − (0.0376 · BMI)]
BIGTT-SI|0-60-1200, 60, and 120 minexp[4.62 − (0.00385 · I0) − (0.000917 · I60) − (0.000760 · I120) − (0.0551 · G0) − (0.0178 · G60) − (0.0524 · G120) − (0.144 · sex) − (0.0380 · BMI)]
BIGTT-SI|full0, 30, 60, 105, 180, and 240 minexp[4.39 − (0.000287 · I0) − (0.000424 · I30) − (0.000848 · I60) − (0.000691 · I105) + (0.000144 · I180) − (0.00282 · I240) − (0.161 · G0) + (0.0357 · G30) − (0.0130 · G60) − (0.0416 · G105) − (0.106 · G180) + (0.169 · G240) − (0.177 · sex) − (0.031 · BMI)]
BIGTT-AIR0-30-1200, 30, and 120 minexp[8.20 + (0.00178 · I0) + (0.00168 · I30) − (0.000383 · I120) − (0.314 · G0) − (0.109 · G30) + (0.0781 · G120) + (0.180 · sex) + (0.032 · BMI)]
BIGTT-AIR0-60-1200, 60, and 120 minexp[8.19 + (0.00339 · I0) + (0.00152 · I60) − (0.000959 · I120) − (0.389 · G0) − (0.142 · G60) + (0.164 · G120) + (0.256 · sex) + (0.038 · BMI)]
BIGTT-AIRfull0, 10, 50, and 140 minexp[7.91 + (0.000898 · I0) + (0.00163 · I10) + (0.00127 · I50) − (0.000966 · I140) − (0.0323 · G0) − (0.0377 · G10) − (0.0985 · G50) + (0.143 · G140) + (0.289 · sex) + (0.036 · BMI)]
  • Sex (female = 0, male = 1); It is serum insulin (picomoles per liter); Gt is plasma glucose (millimoles per liter) at time t min; exp[ ] denotes the exponential function; 0 min is calculated as the mean of values obtained at −10, −5, and 0 min.