Table 1—

Baseline characteristics of the study participants, grouped according to NAFLD status

VariablesWithout fatty liverWith NAFLDP value
n4181,974
Sex (% men)5457<0.001
Age (years)60 ± 465 ± 6<0.001
BMI (kg/m2)26.5 ± 328.3 ± 4<0.001
Diabetes duration (years)7 ± 212 ± 3<0.001
Oral hypoglycemic users (%)67660.80
Insulin users (%)1725<0.001
Antihypertensive drug users (%)6073<0.001
Aspirin users (%)4857<0.001
Lipid-lowering drug users (%)41430.60
Current smokers (%)25270.60
Systolic blood pressure (mmHg)135 ± 10139 ± 12<0.001
Diastolic blood pressure (mmHg)83 ± 785 ± 10<0.001
A1C (%)6.7 ± 0.67.3 ± 1.1<0.001
Triglycerides (mmol/l)1.40 ± 0.61.68 ± 1.0<0.001
HDL cholesterol (mmol/l)1.41 ± 0.31.34 ± 0.4<0.001
LDL cholesterol (mmol/l)3.40 ± 0.43.37 ± 0.40.40
Creatinine (μmol/l)90 ± 1292 ± 140.40
Aspartate aminotransferase (units/l)23 ± 328 ± 10<0.001
ALT (units/l)25 ± 333 ± 12<0.001
Elevated ALT (men >50 units/l; women >35 units/l) (%)014<0.001
ATP III–defined metabolic syndrome (%)7086<0.001
  • Data are means ± SD or proportions. n = 2,392.