Table 2—

Changes in measures of diabetes control, blood pressure control, measures of lipid/lipoproteins control, albumin-to-creatinine ratio, and prevalence of metabolic syndrome among participants seen at year 1

MeasureILIDSEP value
n2,4962,463
Use of diabetes medicines (%)
    Baseline86.5 ± 0.786.5 ± 0.70.93*
    Year 178.6 ± 0.888.7 ± 0.6<0.001*
    Change−7.8 ± 0.62.2 ± 0.5<0.001
Fasting glucose (mg/dl)
    Baseline151.9 ± 0.9153.6 ± 0.90.21
    Year 1130.4 ± 0.8146.4 ± 0.9<0.001
    Change−21.5 ± 0.9−7.2 ± 0.9<0.001
A1C (%)
    Baseline7.25 ± 0.027.29 ± 0.020.26
    Year 16.61 ± 0.027.15 ± 0.02<0.001
    Difference−0.64 ± 0.02−0.14 ± 0.02<0.001
Use of antihypertensive medicines (%)
    Baseline75.3 ± 0.973.7 ± 0.90.23*
    Year 175.2 ± 0.975.9 ± 0.90.54*
    Change−0.1 ± 0.62.2 ± 0.60.02
Systolic blood pressure (mmHg)
    Baseline128.2 ± 0.4129.4 ± 0.30.01
    Year 1121.4 ± 0.4126.6 ± 0.4<0.001
    Change−6.8 ± 0.4−2.8 ± 0.3<0.001
Diastolic blood pressure (mmHg)
    Baseline69.9 ± 0.270.4 ± 0.20.11
    Year 167.0 ± 0.268.6 ± 0.2<0.001
    Change−3.0 ± 0.2−1.8 ± 0.2<0.001
Use of lipid-lowering medicines (%)
    Baseline49.4 ± 1.048.4 ± 1.00.52*
    Year 153.0 ± 1.057.8 ± 1.0<0.001*
    Change3.7 ± 0.89.4 ± 0.8<0.001
LDL cholesterol (mg/dl)
    Baseline112.2 ± 0.4112.4 ± 0.60.78
    Year 1107.0 ± 0.6106.7 ± 0.70.74
    Change−5.2 ± 0.6−5.7 ± 0.60.49
HDL cholesterol (mg/dl)
    Baseline43.5 ± 0.243.6 ± 0.20.80
    Year 146.9 ± 0.344.9 ± 0.2<0.001
    Change3.4 ± 0.21.4 ± 0.1<0.001
Triglycerides (mg/dl)
    Baseline182.8 ± 2.3180.0 ± 2.40.38
    Year 1152.5 ± 1.8165.4 ± 1.9<0.001
    Change−30.3 ± 2.0−14.6 ± 1.8<0.001
Albumin-to-creatinine ratio (>30.0 μg/mg) (%)
    Baseline16.4 ± 0.716.9 ± 0.80.69
    Year 112.5 ± 0.715.4 ± 0.70.005
    Change−3.9 ± 0.6−1.5 ± 0.60.002
Metabolic syndrome (%)
    Baseline93.6 ± 0.594.4 ± 0.50.23
    Year 178.9 ± 0.887.3 ± 0.7<0.001
    Change−14.7 ± 0.8−7.1 ± 0.7<0.001
  • Data are means ± SE or % ± SE.

  • *

    * Logistic regression with adjustment for clinical site.

  • Mantel-Haenszel test with adjustment for clinical site.

  • ANCOVA, with adjustment for clinical site.