Table 4—

RRs of stroke subtypes and diabetes, according to hypertension and obesity status, the Nurses’ Health Study, 1976–2002

VariablesHypertension
Obesity
No diabetes and no hypertensionNo diabetes and hypertensionDiabetes and no hypertensionDiabetes and hypertensionNo diabetes and BMI <30 kg/m2Diabetes and BMI <30 kg/m2Diabetes and BMI ≥30 kg/m2
Total stroke
    Cases1,0651,3191365011,931354267
    Incidence*5420710636586236238
    RR1.02.3 (2.1–2.5)1.9 (1.6–2.3)4.1 (3.6–4.6)1.01.8 (1.6–2.0)1.9 (1.6- 2.3)
Ischemic stroke
    Cases45862580293887201161
    Incidence*23986221340134144
    RR1.02.3 (2.0–2.6)2.5 (2.0–3.2)5.1 (4.3–6.0)1.02.1 (1.8–2.5)2.0 (1.6- 2.6)
Hemorrhagic stroke
    Cases1571009222192011
    Incidence*816716101310
    RR1.01.6 (1.2–2.1)0.9 (0.4–1.7)1.6 (1.0–2.6)1.01.1 (0.7–1.8)1.3 (0.6–2.8)
  • Data are n or RR (95% CI).

  • *

    * Incidence per 100,000 person-years.

  • RRs (with 95% CI) calculated by Cox proportional hazards model adjusted for age, BMI, physical activity, menopausal status and estrogen use, smoking and hypertension, high cholesterol, ischemic heart disease, aspirin use, and alcohol consumption.