Table 1—

The frequency of episodes of biochemical hypoglycemia over the 4-week period and recollected total number of episodes of severe hypoglycemia (SH) during the preceding year

Gold
Clarke
Pedersen-Bjergaard
NormalIAHPNormalIAHPNormalIAHP
From record sheets
    Total biochemical glucose values <3.0 mmol/l3.49 (3.64)7.62 (5.35)0.0033.40 (2.65)7.86 (5.10)0.0013.31 (3.51)5.37 (4.90)0.06
    Biochemical glucose values 2.5–2.9 mmol/l2.38 (2.64)4.14 (2.92)0.022.33 (2.65)4.29 (2.81)0.0062.26 (2.55)3.24 (2.91)0.11
    Biochemical glucose values <2.5 mmol/l1.11 (1.71)3.47 (3.81)0.011.02 (1.67)3.57 (3.80)0.0051.05 (1.51)2.08 (3.11)0.11
    Severe hypoglycemic reactions0 (0)0.1 (0.7)0.100.05 (0.47)0 (0)0.550 (0)0.05 (0.43)0.44
    Autonomic symptoms2.88 (1.06)2.09 (0.99)0.0052.96 (1.05)1.89 (0.79)0.0012.87 (1.08)2.54 (1.09)0.22
    Neuroglycopenic symptoms2.25 (1.02)2.45 (1.14)0.472.29 (1.06)2.35 (1.06)0.832.12 (1.00)2.41 (1.08)0.27
From questionnaire
    Incidence of SH (episodes per patient-year)0.07 (0.32)1.57 (2.82)0.0010.05 (0.29)1.62 (2.80)0.0010 (0)0.76 (1.98)0.04
    Prevalence of SH5%53%5%57%0%26%
  • Data are means (SD).