Table 1—

Clinical details and corneal sensitivity using C-BA and NCCA in control subjects and diabetic patients with increasing neuropathic severity in accordance with NDS, with statistical difference compared with control subjects

Control subjectsNo neuropathyMild neuropathyModerate neuropathySevere neuropathy
n1851492720
Age (years)56 ± 1756 ± 1158 ± 1261 ± 1060 ± 9
Type 1/type 2 diabetes5/4614/356/213/17
Diabetes duration (years)011 ± 1016 ± 1219 ± 1019 ± 12
A1C (%)<6.58.1 ± 1.57.9 ± 1.338.4 ± 1.458.3 ± 1.32
NDS (0–10)01.3 ± 0.93.9 ± 0.77.1 ± 0.99.8 ± 0.4
C-BA (mm)52.28 ± 9.7441.49 ± 17.1634.09 ± 16.32*16.06 ± 14.6111.36 ± 11.42
NCCA (mbar)0.73 ± 0.141.15 ± 0.431.29 ± 0.611.68 ± 0.752.35 ± 1.76§
  • Data are means ± SD unless otherwise indicated.

  • *

    * P < 0.01;

  • P < 0.0001;

  • P < 0.00001;

  • §

    § P < 0.02. mbar, millibar.