Table 2—

Distribution of cutaneous lesions in 212 young type 1 diabetic patients and 196 age- and sex-matched control subjects

LesionsPatients (n = 212)
Control subjects (n = 196)
n (%)Male/ femalen (%)Male/ female
Skin manifestations associated with diabetes
    Xerosis (acquired ichthyosis)47 (22.2)*24/236 (3)3/3
    Diabetic hand5 (2.3)5/00 (0)0
    Rubeosis15 (7.1)6/90 (0)0
    Necrobiosis lipoidica5 (2.3)1/40 (0)0
Infections
    Fungal10 (4.7)3/73 (1.5)3/0
Tinea pedis4 (1.9)2/21 (0.5)1/0
Onychomycosis2 (0.9)2/00 (0)0/0
Candidosis4 (1.9)1/30 (0)0/0
    Viral warts8 (3.7)4/44 (2)2/2
    Bacterial7 (3.3)§5/22 (1)0/2
Impetigo3 (1.4)1/21 (0.5)0/1
Folliculitis3 (1.4)2/11 (0.5)0/1
Skin reactions to insulin therapy
    Lipohypertrophy4 (1.8)2/20 (0)0/0
    Lipoatrophy2 (0.9)0/20 (0)0/0
Other skin disorders
    Acne41 (19.3)20/2331 (15.5)17/14
    Keratosis pilaris27 (11.7)*13/143 (1.5)3/0
    Pityriasis versicolor2 (0.8)2/05 (2.5)4/1
    Café-au-lait macules6 (2.6)4/20 (0)0/0
    Halo nevi4 (1.7)2/20 (0)0/0
    Eczema8 (3.5)3/52 (1)1/1
    Atopic dermatitis1 (0.4)1/01 (0.5)1/0
    Psoriasis2 (0.9)1/10 (0)0/0
    Vitiligo1 (0.4)1/02 (1)2/0
    Alopecia areata2 (0.9)2/00 (0)0/0
    Seborrheic dermatitis6 (2.6)3/37 (3.5)5/2
    Striae dystensae3 (1.3)0/30 (0)0/0
    Dermatitis herpetiformis/gluten enteropathy1 (0.4)0/10 (0)0/0
    Purpuric dermatosis1 (0.4)1/00 (0)0/0
  • * P < 0.01 vs. control patients.

  • Two patients also had Dupuytren contracture.

  • Two patients had tinea corporis(M. canis) and tinea capitis(M. canis), respectively.

  • § A patient with an ingrowing toenail.