Table 2—

Longitudinal development of bone geometry, BMD, and muscle CAS in patients with type 1 diabetes

SD valuesFirst measurementSecond measurement
n4141
Metaphyseal
    TD0.28 ± 1.2−0.01 ± 1.1
    TrabD0.45 ± 1.1*−0.14 ± 1.1
Diaphyseal
    TCSA−0.48 ± 0.9*0.05 ± 1.0
    CCSA−0.32 ± 1.0*0.1 ± 1.0
    MCSA−0.31 ± 0.8*0.09 ± 1.0
    CTH−0.11 ± 0.80.02 ± 0.8
    relCCSA−0.06 ± 0.80.01 ± 0.8
    TD−0.09 ± 0.8−0.06 ± 0.8
    CtD−0.37 ± 1.0*0.16 ± 0.9
    SSI−0.26 ± 1.10.05 ± 1.0
    MslCSA−0.24 ± 1.0−0.05 ± 1.2
BMC-to-MslCSA ratio−0.31 ± 0.90.19 ± 0.9
  • Data are means ± SD.

  • * Significant difference (P < 0.05) for mean values between patients and reference population.

  • Significant difference (P < 0.05) for mean values and between the two measurement time points. CCSA, cortical CSA; CtD, cortical BMD; MCSA, medullary CSA; MslCSA, muscle CSA; SSI, bone strength strain index; TD, total BMD; TrabD, trabecular BMD; TCSA, total bone CSA.