Table 1—

Characteristics and fertility of the women who were first hospitalized for type 1 diabetes at age ≤16 years, 1965–2004, Sweden

Patient characteristicsTotalCalendar year at first hospitalization for type 1 diabetes before 1985Calendar year at first hospitalization for type 1 diabetes during or after 1985
n5,9782,7733,205
Calendar year at entry199019831997
Follow-up duration (years)13.3 ± 8.920.5 ± 6.67.1 ± 5.1
Person-years accumulated79,77456,88822,886
Percentage of women ever experiencing (%)
    Retinopathy*18.734.45.2
    Diabetic nephropathy7.914.81.9
    Neuropathy5.19.41.4
    Cardiovascular complications§4.07.50.9
No. of live births4,01331,24889
Age at first delivery (years)25.826.324.2
  • Data are means or means ± SD unless otherwise indicated.

  • *

    * Retinopathy defined by ICD-7 codes 260.20, 260.21, and 260.29; ICD-8 codes 250.01, 250.02, and 250.03; ICD-9 codes 250E; and ICD-10 codes E10.3, E11.3, E12.3, E13.3, and E14.3. It included aneurysm, inter-retinal edema, intraocular pathologic neovascularization, simplex retinopathy, and proliferative retinopathy.

  • Diabetic nephropathy defined by ICD-7 code 260.30; ICD-8 code 250.40; ICD-9 code 250D; and ICD-10 codes E10.2, E11.2, E12.2, E13.2, and E14.2. It included persistent proteinuria, from microalbuminuria progressing to albuminuria; reduced glomerular filtration rate; and end-stage renal disease.

  • Neuropathy defined by ICD-7 codes 260.40 and 260.49; ICD-8 code 250.05; ICD-9 code 250F; and ICD-10 codes E10.4, E11.4, E12.4, E13.4, and E14.4. It included third nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, a painful polyneuropathy, autonomic neuropathy, thoracoabdominal neuropathy, and unspecified diabetic neuropathy.

  • §

    § Including ischemic heart diseases defined by ICD-7 code 420, ICD-8 codes 410–414, ICD-9 codes 410–414, and ICD-10 codes I20–I25; diseases of arteries, arterioles, and capillaries defined by ICD-7 codes 450–456, ICD-8 codes 440–448, ICD-9 codes 440–448, and ICD-10 codes I70–I79, I98.8, and I99; and surgery for cardiovascular diseases (Swedish codes for surgical procedures 8800–8839 and 8861–8869 before 1997 and PA–PG for 1997 and thereafter).