Table 2—

SFRs and corresponding 95% CIs among women first hospitalized for type 1 diabetes at age ≤16 years, stratified by calendar year and age at first hospitalization, calendar year and age at follow-up, or type of complications,1965–2004, Sweden

Live births
SFR (95% CI)
ExpectedObserved
Total5,0404,0130.80 (0.77–0.82)
Age at first hospitalization for type 1 diabetes
    ≥5 years3933190.81 (0.72–0.91)
    6–10 years1,3721,1220.82 (0.77–0.87)
    11–16 years3,2752,5720.79 (0.76–0.82)
    Ptrend0.30
Calendar period at first hospitalization for type 1 diabetes
    1965–19694082370.58 (0.51–0.66)
    1970–19741,0016860.69 (0.63–0.74)
    1975–19791,4861,1140.75 (0.71–0.80)
    1980–19841,2531,0870.87 (0.82–0.92)
    1985–19896946710.97 (0.89–1.04)
    1990–19941661891.14 (0.98–1.31)
    1995–200431290.92 (0.62–1.32)
    Ptrend<0.01
Calendar period at follow-up
    1965–19792121580.75 (0.63–0.87)
    1980–19891,0146880.68 (0.63–0.73)
    1990–19992,3681,9160.81 (0.77–0.85)
    2000–20041,4461,2510.87 (0.82–0.91)
    Ptrend<0.01
Attained age at follow-up
    16–19 years2051840.90 (0.77–1.04)
    20–24 years1,3271,1580.87 (0.82–0.92)
    25–29 years1,9251,5690.82 (0.78–0.86)
    30–34 years1,2158730.72 (0.67–0.77)
    35–39 years3322090.63 (0.55–0.72)
    40–48 years35200.57 (0.35–0.88)
    Ptrend<0.01
Diabetic retinopathy*
    No4,0093,3640.84 (0.81–0.87)
    Yes1,0306490.63 (0.58–0.68)
Diabetic nephropathy*
    No4,6603,8070.82 (0.79–0.84)
    Yes3802060.54 (0.47–0.62)
Diabetic neuropathy*
    No4,8373,9110.81 (0.78–0.83)
    Yes2031020.50 (0.41–0.61)
Cardiovascular complications*
    No4,9703,9890.80 (0.78–0.83)
    Yes70240.34 (0.22–0.51)
  • The age- and calendar year–matched Swedish women at large were used as a reference population. The SFRs are thus inherently adjusted for attained age and calendar year.

  • *

    * Person-time experienced before the onset of complications was allocated to the complication-negative strata.