Table 1—

Descriptive characteristics of participants (n = 393) at baseline and follow-up: the Medical Research Council Ely Study, 1994–2003

VariableMen (n = 176)
Women (n = 217)
BaselineFollow-upBaselineFollow-up
Age (years)49.7 ± 8.055.3 ± 8.2*49.2 ± 7.454.8 ± 7.5*
Weight (kg)82.5 ± 10.583.6 ± 11.869.0 ± 12.670.7 ± 15.0
Height (cm)175.7 ± 6.2175.5 ± 6.1163.2 ± 6.0163.1 ± 6.0
Fat mass (kg)18.9 ± 5.421.3 ± 6.3*24.8 ± 8.527.0 ± 10.3*
FFM (kg)63.6 ± 6.762.4 ± 7.3*44.2 ± 5.443.6 ± 6.0*
Waist (cm)94.1 ± 8.697.9 ± 9.0*79.4 ± 10.184.7 ± 12.0*
Diastolic BP (mmHg)79.0 ± 10.682.0 ± 10.9*73.0 ± 10.376.0 ± 9.0*
Systolic BP (mmHg)128.5 ± 14.4132.9 ± 15.0*119.6 ± 13.3124.7 ± 13.5*
2-h glucose (mmol/l)¶5.1 (4.9–5.3)6.0 (5.7–6.3)*5.1 (4.9–5.3)5.7 (5.5–6.0)*
Insulin (mU/l)¶41.1 (37.8–44.7)51.4 (46.7–56.6)*35.7 (33.0–38.5)40.9 (37.7–44.8)*
Triglycerides (mmol/l)¶1.3 (1.2–1.4)1.3 (1.2–1.4)1.0 (1.0–1.1)1.1 (1.0–1.2)*
HDL cholesterol (mmol/l)1.33 ± 0.351.31 ± 0.331.66 ± 0.431.61 ± 0.40*
Vo2max(ml · kg FFM−1· min−1)46.8 ± 10.857.9 ± 14.1*43.7 ± 11.955.4 ± 14.2*
PAEE (kJ · kg FFM−1· min−1)0.12 ± 0.050.16 ± 0.07*0.11 ± 0.050.14 ± 0.07*
  • Data are means ± SD or geometric means (95% CI) unless otherwise indicated. No significant time-by-sex interactions were observed.

  • * P < 0.001 and

  • P < 0.01, ANOVA for between-time differences;

  • P < 0.001, ANOVA for between-sex differences. BP, blood pressure.