Table 2—

Independent associations between change in PAEE and individual metabolic risk factors and clustered metabolic risk 5.6 years later, as well as between change in fat mass and individual metabolic risk factors and clustered metabolic risk 5.6 years later

OutcomeChange in PAEEPChange in FMP
Diastolic BP (mmHg)−0.88 (−1.79 to 0.04)0.060.04 (0.03 to 0.06)<0.0001
Systolic BP (mmHg)−0.68 (−1.62 to 0.27)0.160.04 (0.02 to 0.06)<0.0001
2-h glucose (mmol/l)−1.40 (−2.70 to −0.10)0.0350.03 (0.008 to 0.05)0.008
Insulin (mU/l)−1.32 (−2.46 to −0.18)0.0230.06 (0.04 to 0.08)<0.0001
Triglycerides (mmol/l)−0.88 (−1.76 to −0.003)0.0490.03 (0.02 to 0.05)<0.0001
HDL cholesterol (mmol/l)0.21 (−0.56 to 0.98)0.60−0.01 (−0.02 to 0.003)0.14
Clustered metabolic risk−0.92 (−1.47 to −0.38)0.0010.04 (0.03 to 0.04)<0.0001
  • Data are regression coefficients (95% CI), which represent the expected change in the outcome (expressed as a standardized Z score) for a 1-unit increase in either change in PAEE or change in fat mass (FM); n = 393. Fasting insulin, triglycerides, and 2-h glucose are log transformed. Data are adjusted for age, sex, smoking status, aerobic fitness, baseline phenotype, and duration of follow-up. Change in PAEE and change in fat mass are included in the same model. BP, blood pressure.