Table 1—

Descriptive statistics of demographic variables, covariates, and outcome variables

Sample sizeMean ± SDInterquartile range
Conventional risk factors
    Age (years)1,06339.2 ± 7.010.0
    DCCT experimental group (%)1,06351
    Type 1 diabetes duration (years)1,06317.5 ± 4.87.7
    A1C (% of hemoglobin)1,0458.2 ± 1.31.7
    Male sex (%)1,06355
    Smoker (%)1,04219
    Systolic blood pressure (mmHg)1,045120.0 ± 13.918.0
    Diastolic blood pressure (mmHg)1,04575.0 ± 9.312.0
    Height (cm)1,046172.5 ± 9.413.7
    Weight (kg)1,04681.3 ± 15.521.7
    BMI (kg/m2)1,04427.2 ± 4.25.1
    Natural waist-to-hip ratio1,0450.8 ± 0.10.1
    Total cholesterol (mg/dl)1,027189 ± 35.344.0
    HDL cholesterol (mg/dl)1,02756 ± 14.719.0
    LDL cholesterol (mg/dl)1,021115 ± 30.539
    Triglycerides (mg/dl)1,02789 ± 63.351.0
Biomarkers
    PAI-1 activity (IU/ml)9284.5 ± 6.94.5
    PAI-1 mass (ng/ml)99032.2 ± 24.830.6
    sE-Selectin (ng/ml)75258.7 ± 35.738.4
    sICAM-1 (ng/ml)812332.4 ± 123.7158.6
    sVCAM-1 (ng/ml)782685.8 ± 442.4418.1
    tPA activity (IU/ml)9881.0 ± 0.50.5
    tPA mass (ng/ml)9646.3 ± 5.04.3
    Fibrinogen (mg/dl)911309.5 ± 106.9128.0
    CRP (mg/l)9513.1 ± 4.63.0
Outcomes
    AER (mg/24 h)1,02087 ± 441.714.4
    Micro-/macroalbuminuria (AER >40 mg/24 h) (%)1,02014
    Internal IMT year 6 (units)9580.7 ± 0.30.1
    Common IMT at year 6 ( units)9700.6 ± 0.10.2