Table 2—

β-Coefficients for the clinical, clinical + biological, and clinical + biological + genetic equations: the DESIR study

Clinical equation
Clinical + biological equation
Clinical + biological + genetic equation
n = 1,860 men (140 with diabetes) and n = 1,954 women (63 with diabetes)
n = 1,860 men (140 with diabetes) and n = 1,954 women (63 with diabetes)
n = 1,655 men (128 with diabetes) and n = 1,740 women (58 with diabetes)
βPβPβP
Men
    Intercept−10.45−10.5310.91
    Current smoker0.720.00020.880.00010.940.0001
    Waist circumference (cm)0.0810.00010.0600.00010.0600.0001
    Hypertension*0.500.01
    Fasting glucose (mmol/l)10.150.000110.170.0001
    Fasting glucose224.160.00222.420.007
    GGT (IU/l)0.390.010.420.007
    Number of TCF7L2 and IL6 deleterious alleles0.140.2
    AROC statistic0.7330.8500.851
    Hosmer-Lemeshow fit test0.70.80.1
Women
    Intercept−11.81−18.91−20.43
    Diabetes in the family1.090.00010.800.010.750.02
    Waist circumference (cm)0.0950.0001
    BMI (kg/m2)4.380.00014.690.0001
    Hypertension*0.640.03
    Fasting glucose (mmol/l)9.660.0019.350.001
    Fasting glucose223.890.0622.390.08
    Triglycerides (mmol/l)0.950.0030.860.01
    Number of TCF7L2 amd IL6 deleterious alleles0.360.04
    AROC statistic0.8390.9170.912
    Hosmer-Lemeshow fit test0.60.90.8
  • * Systolic/diastolic blood pressure ≥140/90 mmHg or medication for hypertension.

  • Fasting glucose, GGT, BMI, and triglycerides were log transformed.