Table 1—

Characteristics of participants who were adolescents at entry into the DCCT

DCCT baseline (1983–1989)
EDIC year 12 (2005)
IntensiveConventionalIntensiveConventional
n82938293
Sex (% female)50625062
Race (% white)99929992
Age (years)16 ± 216 ± 236 ± 335 ± 3
College graduate (%)003742
Marital status (%)
    Never married100992119
    Married/remarried016968
    Separated/divorced/widowed001013
Occupation (%)
    Professional/technical105341
    Unemployed/retired0029
Severe nonproliferative diabetic retinopathy (%)001123
Duration (years)5 ± 35 ± 425 ± 424 ± 4
A1C9.5 ± 1.79.4 ± 1.97.8 ± 1.57.9 ± 1.6
Visual acuity (%)64
Peripheral neuropathy (%)§211733
Blood pressure
    Systolic (mmHg)112 ± 10109 ± 11117 ± 13115 ± 13
    Diastolic (mmHg)71 ± 970 ± 974 ± 975 ± 9
    Treated hypertension1930
Lipids
    Total cholesterol166 ± 32165 ± 31179 ± 34185 ± 37
    LDL cholesterol102 ± 30101 ± 28109 ± 28113 ± 30
    Lipid-lowering medication1917
Current cigarette smoker (%)9111518
Symptom Check List-90R
    Mean depression T score45 ± 1047 ± 1149 ± 1049 ± 12
Verbal IQ110 ± 12108 ± 12
Full-scale IQ111 ± 11110 ± 12
  • Data are means ± SD.

  • DCCT baseline value is the eligibility value.

  • At DCCT baseline, all patients had visual acuity of 20/32 or better. In EDIC, a Snellen value of 20/40 or worse in at least one eye was recorded.

  • § The DCCT baseline definition is pain or numbness in hands only, taken from the Neurological History and Examination form. The EDIC definition is pain or numbness in hands or feet, taken from the Annual Medical History and Examination form.

  • Data were not collected in DCCT.

  • Data were not collected in EDIC. Mean value is 100, with SD of 15. The Wechsler Adult Intelligence Scale was administered for patients aged ≥16 years (58% intensive and 55% conventional), whereas the Wechsler Intelligence Scale for Children was given for participants aged <16 years (43% intensive and 45% conventional).