Table 2—

Cox proportional hazard models, all participants

χ2d.f.P valueHR (95% CI)
Univariate models*
    FPIR (pmol/l)54.341<0.00010.997 (0.996–0.998)
    Additional antibodies21.681<0.00011.94 (1.43–2.62)
    120-min glucose (mmol/l)25.001<0.00011.37 (1.21–1.54)
    Age (years)7.8710.0060.94 (0.90–0.98)
    Height SDS0.4510.8311.02 (0.83–1.26)
    Weight SDS0.6310.4281.09 (0.88–1.34)
    BMI SDS0.4610.4681.07 (0.88–1.30)
    Pubertal stage10.0230.028
Tanner 5§1
Tanner 010.0082.33 (1.25–4.33)
Tanner 1–210.3701.40 (0.67–2.90)
Tanner 3–410.1751.97 (0.74–5.28)
    HOMA2-IR0.2710.6020.90 (0.61–1.33)
Multivariate model*
    FPIR (pmol/l)45.861<0.00010.998 (0.995–0.998)
    Additional antibodies17.641<0.00011.85 (1.36–2.52)
    120-min glucose (mmol/l)14.741<0.00011.27 (1.13–1.43)
    HOMA2-IR3.1110.0561.43 (0.99–2.06)
  • * All models controlled for treatment group.

  • Hazard ratio per incremental unit.

  • Hazard ratio per antibody in addition to ICA.

  • § Reference group.