Table 3—

Multivariate Cox proportional hazard models in subgroups defined by FPIR

χ2d.f.SignificanceHR (95% CI)
Low FPIR (below age-adjusted 10th centile)
    FPIR (pmmol/l)*10.0810.0010.994 (0.990–0.998)
    Additional antibodies9.2410.0021.82 (1.20–2.76)
    120-min glucose (mmol/l)*5.6410.0041.20 (1.03–1.39)
    HOMA2-IR*5.0510.0253.67 (1.12–11.10)
Preserved FPIR (above age-adjusted 10th centile)
    120-min glucose (mmol/l)*9.6310.0011.39 (1.14–1.70)
    FPIR (pmol/l)*7.0710.0190.998 (0.996–1.000)
    Additional antibodies6.5710.0161.80 (1.12–2.89)
    HOMA2-IR*0.9810.2951.27 (0.91–2.00)
  • All models controlled for treatment group.

  • * Hazard ratio per incremental unit.

  • Hazard ratio per antibody in addition to ICAs.