Table 1—

Characteristics of offspring of mothers with mutations in the GCK gene and characteristics of 118 babies in EFSOCH born at 38 weeks of gestation as a comparison group

GCK NNGCK NMP valueEFSOCH
n1825118
Placental weight (g)720 (650–834)610 (540–788)0.04600 (500–700)
Placental ratio (%)21.4 (17.0–22.9)20.7 (18.7–24.4)0.6318.5 (16.4–20.6)
Birth weight (kg)3.82 (3.25–4.32)3.36 (2.59–3.71)0.0073.20 (2.94–3.53)
Male sex10 (56)13 (52)0.8265 (55)
Gestation (weeks)38.0 (37.0–40.0)38.0 (38.0–40.5)0.3638
  • Data are presented as median (interquartile range) or n (%). P values refer to the differences between GCK NN and GCK NM groups.