Table 1—

Association between retinal vascular caliber and 5-year incident retinopathy in the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study

nIncidence (%)Age- and sex-adjusted OR (95% CI)PMultivariable-adjusted OR (95% CI)*P
Retinal arteriolar caliber
    All participants
Narrower 75% (<191.0 μm)6792.71.01.0
Widest 25% (≥191.0 μm)2274.03.62 (1.42–9.25)0.0074.79 (1.57–14.58)0.006
    Participants with diabetes
Narrower 75% (<189.0 μm)1877.01.01.0
Widest 25% (≥189.0 μm)6311.13.52 (1.12–10.99)0.0315.21 (1.24–21.88)0.024
Retinal venular caliber
    All participants
Narrower 75% (<220.9 μm)6793.41.01.0
Widest 25% (≥220.9 μm)2271.80.68 (0.22–2.12)0.5010.77 (0.23–2.60)0.670
    Participants with diabetes
Narrower 75% (<219.0 μm)1879.11.01.0
Widest 25% (≥219.0 μm)634.80.59 (0.15–2.28)0.4420.47 (0.09–2.40)0.364
  • *

    * Adjusted for age, sex, systolic blood pressure, A1C, total cholesterol, and BMI. Models for arteriolar caliber were adjusted for venular caliber and vice versa.