Table 1—

Annual number of singleton births, mean maternal age, and prevalence of preexisting diabetes per 100 births by maternal age and race/ethnicity among 209,287 births by year, Kaiser Permanente Southern California, 1999–2005

1999200020012002200320042005Ptrend*
No. births32,08931,37729,98029,87729,59828,13528,231
Mean age (years)28.228.328.528.829.029.129.1
No. with diabetes245333315377451526537
    13–19 years0.11 (0.07)0.25 (0.10)0.14 (0.08)0.21 (0.11)0.51 (0.17)0.17 (0.10)0.55 (0.17)0.0106
    20–24 years0.36 (0.07)0.48 (0.09)0.41 (0.08)0.58 (0.10)0.66 (0.11)0.87 (0.13)0.72 (0.12)0.0001
    25–29 years0.59 (0.08)0.70 (0.09)0.85 (0.10)0.92 (0.10)1.19 (0.12)1.40 (0.13)1.29 (0.13)<0.0001
    30–34 years0.95 (0.11)1.44 (0.13)1.23 (0.12)1.50 (0.13)1.83 (0.15)2.34 (0.17)2.36 (0.17)<0.0001
    35–39 years1.39 (0.18)1.98 (0.22)1.87 (0.21)2.30 (0.23)2.61 (0.24)3.00 (0.26)3.43 (0.27)<0.0001
    ≥40 years2.86 (0.54)3.13 (0.57)3.62 (0.58)3.32 (0.54)3.35 (0.54)4.66 (0.66)4.08 (0.60)0.0425
Race/ethnicity
    Non-Hispanic white
        Crude0.63 (0.08)0.89 (0.10)0.82 (0.10)1.14 (0.12)1.23 (0.13)1.53 (0.14)1.48 (0.15)<0.0001
        Age-adjusted0.61 (0.02)0.87 (0.02)0.75 (0.02)1.09 (0.02)1.15 (0.02)1.42 (0.03)1.38 (0.03)<0.0001
    Hispanic
        Crude0.75 (0.07)1.13 (0.08)1.05 (0.08)1.22 (0.09)1.66 (0.10)1.98 (0.12)1.92 (0.11)<0.0001
        Age-adjusted0.89 (0.02)1.29 (0.02)1.15 (0.02)1.27 (0.02)1.72 (0.03)2.04 (0.03)1.95 (0.03)<0.0001
    Black
        Crude0.87 (0.16)1.39 (0.21)1.44 (0.21)1.59 (0.23)1.66 (0.24)2.11 (0.28)2.59 (0.31)<0.0001
        Age-adjusted0.96 (0.02)1.53 (0.03)1.52 (0.03)1.62 (0.03)1.68 (0.03)2.23 (0.03)2.77 (0.04)<0.0001
    Asian/Pacific Islander
        Crude1.07 (0.18)0.95 (0.17)1.20 (0.19)1.48 (0.21)1.47 (0.20)2.02 (0.24)2.12 (0.25)<0.0001
        Age-adjusted0.96 (0.02)0.78 (0.02)0.98 (0.02)1.15 (0.02)1.24 (0.02)1.70 (0.03)1.73 (0.03)<0.0001
    Other races
        Crude0.95 (0.47)0.26 (0.26)1.17 (0.58)1.04 (0.52)1.63 (0.66)1.08 (0.54)1.97 (0.56)0.0431
        Age-adjusted1.05 (0.02)0.35 (0.01)1.34 (0.03)0.91 (0.02)1.68 (0.03)1.25 (0.02)2.14 (0.03)0.0710
All women
    Crude0.76 (0.05)1.06 (0.06)1.05 (0.06)1.26 (0.06)1.52 (0.07)1.87 (0.08)1.90 (0.08)<0.0001
    Age-adjusted0.81 (0.02)1.10 (0.02)1.06 (0.02)1.25 (0.02)1.50 (0.03)1.81 (0.03)1.83 (0.03)<0.0001
    Age- and race/ethnicity-adjusted0.81 (0.02)1.10 (0.02)1.06 (0.02)1.24 (0.02)1.50 (0.03)1.82 (0.03)1.82 (0.03)<0.0001
  • Data are prevalence per 100 (SEM).

  • *

    * P values derived from Poisson regression models using pre-existing diabetes as the outcome variable and year as a continuous variable in the model after adjustment for other variables specified for the row.

  • Preexisting diabetes.