Table 1—

CVD factors among NHANES III and NHANES 1999–2004 participants 20 years of age and older with and without stage 3 CKD

Stage 3 CKD
No stage 3 CKD
NHANES IIINHANES 1999–2004Age-adjusted P for time-period differenceNHANES IIINHANES 1999–2004Age-adjusted P for time-period difference
n88299413,49911,459
Mean age (years)71.5 (0.8)70.7 (0.6)0.42444.0 (0.4)45.0 (0.3)0.050
Male sex36.6 (3.0)36.1 (1.4)0.83949.1 (0.4)49.9 (0.4)0.552
Black race7.0 (0.8)6.7 (0.9)0.79210.4 (0.6)10.6 (1.0)0.878
Mean SBP (mmHg)140.8 (1.1)138.9 (0.9)0.303120.2 (0.4)122.8 (0.4)0.001
Mean DBP (mmHg)72.9 (0.6)68.3 (0.6)<0.00173.2 (0.3)72.7 (0.2)<0.001
On anti-HT medications*71.0 (2.5)79.0 (2.2)0.01650.4 (1.2)60.0 (1.6)<0.001
Mean BMI (kg/m2)27.6 (0.2)28.7 (0.3)0.01326.5 (0.1)28.0 (0.1)<0.001
Mean total cholesterol (mg/dl)232.1 (3.0)206.8 (1.8)<0.001203.1 (0.8)202.2 (0.7)<0.001
On cholesterol-lowering medication22.9 (3.9)61.8 (2.5)<0.00113.5 (1.0)38.3 (1.4)<0.001
Glycated hemoglobin (%)6.03 (0.07)5.83 (0.04)0.0135.35 (0.02)5.46 (0.02)0.405
Cigarette smokers12.4 (1.8)8.1 (1.5)0.03329.1 (0.8)21.6 (0.7)<0.001
Obese31.6 (2.2)32.2 (1.6)0.75522.1 (0.7)29.8 (0.8)<0.001
Hypertension72.7 (2.0)70.5 (1.8)0.62221.6 (0.8)27.2 (0.8)<0.001
High cholesterol46.8 (2.6)44.4 (2.0)0.32620.5 (0.6)24.4 (0.6)<0.001
Diabetes
    Diagnosed13.0 (1.3)16.8 (1.8)0.0933.3 (0.2)5.0 (0.3)0.039
    Undiagnosed10.6 (2.1)10.3 (1.7)0.5833.2 (0.3)3.6 (0.3)0.882
  • Data are n (%) unless otherwise indicated.

  • *

    * Among participants with a diagnosis of hypertension;

  • among participants with a diagnosis of high cholesterol. All P values (except age) for comparing mean levels and prevalence between NHANES III and NHANES 1999–2004 are age adjusted. DBP, diastolic blood pressure; HT, hypertensive; SBP, systolic blood pressure.