Table 2—

CVD risk factors among NHANES III and NHANES 1999–2004 participants 20 years of age and older with and without albuminuria

Albuminuria
No albuminuria
NHANES IIINHANES 1999–2004Age-adjusted P for time-period differenceNHANES IIINHANES 1999–2004Age-adjusted P for time-period difference
n1,8101,71113,40611,067
Mean age (years)57.3 (0.9)56.3 (0.7)0.38044.2 (0.5)45.6 (0.3)0.016
Male sex43.6 (2.3)47.9 (1.3)0.05351.2 (0.4)50.3 (0.4)0.778
Black race15.8 (1.2)14.3 (1.6)0.410.4 (0.6)10.4 (1.0)1.00
Mean SBP (mmHg)137.9 (1.1)138.2 (0.8)0.346120.0 (0.4)122.6 (0.4)0.021
Mean DBP (mmHg)77.0 (0.5)74.2 (0.6)<0.00173.1 (0.3)72.4 (0.2)<0.001
On anti-HT medications60.0 (2.2)66.8 (2.0)0.00551.5 (1.3)61.4 (1.5)<0.001
Mean BMI (kg/m2)28.0 (0.3)29.3 (0.4)<0.00126.5 (0.1)27.9 (0.1)<0.001
Mean total cholesterol (mg/dl)220.3 (1.7)206.3 (2.1)<0.001203.4 (0.9)202.4 (0.6)<0.001
On cholesterol lowering medications18.0 (2.8)51.8 (2.8)<0.00111.9 (1.0)39.6 (1.6)<0.001
Glycated hemoglobin (%)6.24 (0.08)6.16 (0.05)0.2675.31 (0.02)5.41 (0.01)1.00
Cigarette smokers27.0 (1.8)20.5 (1.4)0.00228.8 (0.9)20.7 (0.7)<0.001
Obese32.2 (1.7)39.3 (2.2)0.00122.0 (0.6)29.0 (0.7)<0.001
Hypertension57.6 (2.3)57.4 (1.8)0.49621.2 (0.8)27.4 (0.8)<0.001
High cholesterol37.3 (1.9)33.6 (1.7)0.65823.5 (0.7)25.1 (0.6)0.044
Diabetes
    Diagnosed18.0 (1.3)21.6 (1.1)0.012.4 (0.2)4.3 (0.2)0.014
    Undiagnosed11.6 (1.9)14.1 (2.3)0.8223.0 (0.3)2.9 (0.3)0.861
  • Data are n (%) unless otherwise indicated. All P values (except age) for comparing mean levels and prevalence between NHANES III and NHANES 1999–2004 are age adjusted. DBP, diastolic blood pressure; HT, hypertensive; SBP, systolic blood pressure.