Table 2—

Multiple logistic regression analyses of the associations of adipokines with incident type 2 diabetes: the Sandy Lake Health and Diabetes Project

Independent variableSDModel 1*
Model 2
Model 3
OR (95% CI)POR (95% CI)POR (95% CI)P
Adiponectin0.490.57 (0.44–0.73)<0.0010.63 (0.48–0.83)0.0010.68 (0.51–0.90)0.007
Leptin0.922.05 (1.44–2.90)<0.0011.50 (1.02–2.21)0.040.97 (0.58–1.62)0.89
CRP1.411.48 (1.13–1.95)0.0051.29 (0.96–1.73)0.091.05 (0.76–1.46)0.77
IL-61.001.23 (0.96–1.57)0.101.11 (0.84–1.45)0.471.03 (0.78–1.36)0.84
SAA0.881.17 (0.92–1.48)0.201.14 (0.88–1.49)0.331.07 (0.81–1.41)0.62
A/L1.110.43 (0.31–0.59)<0.0010.54 (0.37–0.77)<0.0010.66 (0.42–1.02)0.06
  • Data are OR (95% CI) per 1-SD change. n = 479 for models including adiponectin and n = 490 for models including leptin, CRP, IL-6, or SAA.

  • *

    * Adjusted for age and sex.

  • Adjusted for model 1 variables + triglycerides, HDL cholesterol, hypertension, and impaired glucose tolerance.

  • Adjusted for model 2 variables + waist circumference.