Table 2—

RRs (95% CIs) for nontraumatic LEAs, according to calendar period at follow-up, sex, and attained age, among patients hospitalized at least once for type 1 diabetes, 1975–2004, Sweden

All nontraumatic LEAs
Amputation above knee
Amputation below knee but above ankle
Amputation below ankle
Obs*RR (95% CI)ObsRR (95% CI)ObsRR (95% CI)ObsRR (95% CI)
Calendar period at follow-up
    1975–1999307Reference21Reference132Reference154Reference
    2000–20041580.6 (0.5–0.8)80.5 (0.2–1.3)610.5 (0.4–0.7)890.7 (0.5–0.9)
Sex
    Male264Reference11Reference111Reference142Reference
    Female2010.7 (0.5–0.8)181.5 (0.7–3.1)820.6 (0.5–0.8)1010.6 (0.5–0.8)
Attained age (years)
    <40126Reference12Reference37Reference77Reference
    40–492049.7 (7.7–12.1)125.8 (2.6–12.9)9415.4 (10.5–22.6)987.5 (5.6–10.1)
    50–5912121.3 (16.5–27.5)47.4 (2.3–23.4)5937.1 (24.4–56.5)5816.1 (11.3–22.8)
    ≥601442.9 (24.3–75.6)133.7 (4.0–280.8)334.7 (10.5–114.7)1045.9 (23.2–90.9)
Ptrend<0.0001<0.0001<0.0001<0.0001
  • Variables listed in the table were mutually adjusted.

  • * Obs, number of observed nontraumatic LEAs in each category.